D Scott Wilbur Selected Research

Streptavidin

11/2016	Comparative Analysis of Bispecific Antibody and Streptavidin-Targeted Radioimmunotherapy for B-cell Cancers.
12/2011	Pretargeted radioimmunotherapy using genetically engineered antibody-streptavidin fusion proteins for treatment of non-hodgkin lymphoma.
11/2010	Conventional and pretargeted radioimmunotherapy using bismuth-213 to target and treat non-Hodgkin lymphomas expressing CD20: a preclinical model toward optimal consolidation therapy to eradicate minimal residual disease.
7/2010	Design and synthesis of bis-biotin-containing reagents for applications utilizing monoclonal antibody-based pretargeting systems with streptavidin mutants.
5/2009	A comparative analysis of conventional and pretargeted radioimmunotherapy of B-cell lymphomas by targeting CD20, CD22, and HLA-DR singly and in combinations.
2/2008	Eradication of disseminated leukemia in a syngeneic murine leukemia model using pretargeted anti-CD45 radioimmunotherapy.
1/2008	Streptavidin in antibody pretargeting. 5. chemical modification of recombinant streptavidin for labeling with the alpha-particle-emitting radionuclides 213Bi and 211At.
9/2007	Pretargeted radioimmunotherapy for B-cell lymphomas.
7/2006	Comparison of a tetravalent single-chain antibody-streptavidin fusion protein and an antibody-streptavidin chemical conjugate for pretargeted anti-CD20 radioimmunotherapy of B-cell lymphomas.
1/2005	Role of biotin-binding affinity in streptavidin-based pretargeted radioimmunotherapy of lymphoma.

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D Scott Wilbur Research Topics

Disease

28	Neoplasms (Cancer) 01/2022 - 05/2002
15	Lymphoma (Lymphomas) 01/2017 - 03/2003
9	B-Cell Lymphoma (Lymphoma, B Cell) 01/2017 - 03/2003
8	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/2017 - 03/2003
6	Leukemia 12/2020 - 02/2008
3	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/2020 - 07/2011
3	Myeloid Leukemia (Leukemia, Myelocytic) 12/2020 - 07/2011
3	Hematologic Neoplasms (Hematological Malignancy) 01/2018 - 01/2014
2	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 12/2021
2	Multiple Myeloma 10/2019 - 01/2018
2	Ascites 11/2015 - 07/2002
2	Residual Neoplasm 03/2015 - 11/2010
1	Prostatic Neoplasms (Prostate Cancer) 01/2021
1	Blood-Borne Infections 11/2019
1	Infertility (Sterility) 01/2018
1	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2016
1	Burkitt Lymphoma (Burkitt's Lymphoma) 03/2003

Drug/Important Bio-Agent (IBA)

14	Radioisotopes (Radionuclides)IBA 01/2022 - 05/2002
12	Biotin (Vitamin H)FDA Link 01/2018 - 05/2002
12	StreptavidinIBA 11/2016 - 05/2002
10	Proteins (Proteins, Gene)FDA Link 01/2021 - 07/2006
9	procaine isothiocyanate (PRIT)IBA 12/2020 - 06/2007
7	AntibodiesIBA 01/2018 - 03/2003
5	Astatine-211IBA 01/2021 - 06/2011
5	DOTA-biotin (90Y-DOTA-biotin)IBA 12/2020 - 03/2003
5	Monoclonal AntibodiesIBA 03/2015 - 09/2007
4	Immunoconjugates (Immunoconjugate)IBA 10/2014 - 06/2007
4	Indicators and Reagents (Reagents)IBA 06/2011 - 05/2004
3	AntigensIBA 12/2021 - 06/2007
3	GalactosamineIBA 07/2010 - 07/2006
3	HLA-DR Antigens (HLA-DR)IBA 05/2009 - 06/2007
2	1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acidIBA 10/2014 - 03/2003
2	AcetylgalactosamineIBA 05/2009 - 09/2007
2	Surface Antigens (Surface Antigen)IBA 05/2009 - 06/2007
2	AcidsIBA 09/2007 - 06/2007
1	Fetal Proteins (Fetoprotein)IBA 01/2022
1	GlypicansIBA 12/2021
1	alpha-Fetoproteins (alpha-Fetoprotein)IBA 12/2021
1	Urea (Carbamide)FDA LinkGeneric 01/2021
1	human FOLH1 proteinIBA 01/2021
1	Lysine (L-Lysine)FDA Link 01/2021
1	Glutamic Acid (Glutamate)FDA Link 01/2021
1	PyrogensIBA 01/2018
1	Protons (Proton)IBA 06/2017
1	venetoclaxIBA 01/2017
1	Cesium-137IBA 01/2017
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2016
1	fludarabineIBA 01/2016
1	HLA Antigens (Human Leukocyte Antigens)IBA 01/2016
1	EnzymesIBA 11/2015
1	BismuthIBA 07/2011
1	Bismuth-213IBA 11/2010
1	Single-Chain AntibodiesIBA 07/2010
1	Neoplasm Antigens (Tumor Antigens)IBA 06/2007
1	Transaminases (Aminotransferases)IBA 07/2002

Therapy/Procedure

19	Radioimmunotherapy 12/2020 - 05/2002
15	Therapeutics 01/2022 - 05/2002
4	Cell Transplantation 01/2018 - 07/2006
3	Radiotherapy 01/2017 - 09/2007
3	Drug Therapy (Chemotherapy) 05/2013 - 09/2007
1	Aftercare (After-Treatment) 01/2022
1	Precision Medicine 12/2021
1	Injections 12/2020
1	Euthanasia (Mercy Killing) 12/2020
1	Hematopoietic Stem Cell Transplantation 05/2013
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 05/2013
1	Chemoradiotherapy 09/2007
1	Stem Cell Transplantation 09/2007